I-Horseshoe crab, isidalwa sasolwandle esingeyona ingozi nesakudala, idlala indima ebalulekile emvelweni, ukuthi ingaba ukudla kwezimfudu noshaka kanye nezinyoni zasogwini.Njengoba kutholakala imisebenzi yegazi layo eliluhlaza, inkalankala ye-horseshoe nayo iba ithuluzi elisha elisindisa ukuphila.
Ngawo-1970, ososayensi bathola ukuthi igazi eliluhlaza okwesibhakabhaka lenkalankala yehhashi lalijika uma selichayeke kubhaktheriya we-E. coli.Kungenxa yokuthi i-amebocyte egazini lenkalankala eluhlaza okwesibhakabhaka ingasabela nge-endotoxins, izinto ezinobuthi ezikhishwe i-E. coli namanye amagciwane angenayo igremu angaveza izimpawu ezinzima kubantu abaveziwe njengemfiva noma i-stroke eyopha kakhulu.
Kungani igazi eliluhlaza lenkalankala yehhashi linemisebenzi enjalo?Kungase kube imiphumela yokuziphendukela kwemvelo.Indawo yokuhlala yenkalankala yehhashi igcwele amagciwane, futhi inkalankala yehhashi ibhekene nosongo oluqhubekayo lokutheleleka.I-amebocyte egazini elihlaza okwesibhakabhaka lenkalankala yehhashi idlala indima ebalulekile ekulweni nokutheleleka, ukuthi ngenxa ye-amebocyte, igazi layo eliluhlaza lingabopha ngokushesha futhi livimbe nxazonke zesikhunta, amagciwane kanye nama-endotoxins amagciwane.Isimiso sokuzivikela komzimba senkalankala yehhashi esenza igazi lenkalankala libe usizo embonini yethu yezokwelapha.
Ngenxa yekhono layo lokubopha nokujiyisa, igazi elihlaza okwesibhakabhaka lenkalankala yehhashi lisetshenziselwa ukukhiqiza i-limulus amebocyte lysate, uhlobo lwe-lyophilized amebocyte lysate.Futhi imikhiqizo ekhiqizwa nge-amebocyte evela ku-horseshoe crab ngaphansi kwezindlela ezahlukene iyathuthukiswa.Njengamanje, kunezindlela ezintathu ezisetshenziswayo ukuthola i-endotoxin yebhaktheriya ngokusebenzisa i-lyophilized amebocyte lyate, okungukuthi indlela ye-gel-clot, indlela ye-turbidimetric kanye nendlela ye-chromogenic.I-Xiamen Bioendo Technology Co., Ltd. abakhiqizi be-lyophilized amebocyte lysate ngalawa masu amathathu.
Isikhathi sokuthumela: Feb-28-2019
